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Clinical and Diagnostic Laboratory Immunology, May 2003, p. 469-472, Vol. 10, No. 3
1071-412X/03/$08.00+0     DOI: 10.1128/CDLI.10.3.469-472.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Effect of Glycosphingolipids Purified from Leishmania (Leishmania) amazonensis Amastigotes on Human Peripheral Lymphocytes

Selma Giorgio,1 Marcia Regina M. Santos,2 Anita H. Straus,3 Helio K. Takahashi,3 and Clara Lúcia Barbiéri2*

Department of Parasitology, Instituto de Biologia, UNICAMP, Campinas,1 Department of Microbiology, Immunology and Parasitology,2 Department of Biochemistry, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, São Paulo, 04023-062, Brazil3

Received 6 November 2002/ Returned for modification 21 January 2003/ Accepted 12 March 2003

The effect of purified glycosphingolipids from Leishmania (Leishmania) amazonensis on human lymphoproliferation, on expression of human lymphocyte and monocyte markers (CD3, CD4, CD8, CD14, CD19, and CD45), and on lymphocyte protein kinase C activity was analyzed.

* Corresponding author. Mailing address: Department of Microbiology, Immunology and Parasitology, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Botucatu, 862 6 andar, São Paulo, SP 04023-062, Brazil. Phone: 55-11-5576-4532. Fax: 55-11-5571-1095. E-mail: barbiericl{at}ecb.epm.br.

Clinical and Diagnostic Laboratory Immunology, May 2003, p. 469-472, Vol. 10, No. 3
1071-412X/03/$08.00+0     DOI: 10.1128/CDLI.10.3.469-472.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.





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Copyright © 2003 by the American Society for Microbiology. All rights reserved.