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Clinical and Diagnostic Laboratory Immunology, November 2003, p. 1147-1148, Vol. 10, No. 6
1071-412X/03/$08.00+0     DOI: 10.1128/CDLI.10.6.1147-1148.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Simplified Serological Diagnosis of Endocarditis Due to Coxiella burnetii and Bartonella

J. M. Rolain, C. Lecam, and D. Raoult*

Unité des Rickettsies, CNRS UMR 6020, Faculté de Médecine, Université de la Méditerranée, 13385 Marseille Cedex 05, France

Received 19 June 2003/ Returned for modification 6 August 2003/ Accepted 29 August 2003

We tested a single-step serological assay against Coxiella burnetii and Bartonella species and found a sensitivity of 100%, and a positive predictive value of 98% for the diagnosis of blood culture-negative endocarditis (BCNE). This assay should be considered as a possible commercial test for the diagnosis of BCNE.

* Corresponding author. Mailing address: Unité des Rickettsies, CNRS UMR 6020, IFR48, Faculté de Médecine, Université de la Méditerranée, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France. Phone: (33) 4 91 38 55 17. Fax: (33) 4 91 83 03 90. E-mail: Didier.Raoult{at}medecine.univ-mrs.fr.

Clinical and Diagnostic Laboratory Immunology, November 2003, p. 1147-1148, Vol. 10, No. 6
1071-412X/03/$08.00+0     DOI: 10.1128/CDLI.10.6.1147-1148.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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