CVI
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Yasui, H.
Right arrow Articles by Shida, K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yasui, H.
Right arrow Articles by Shida, K.

 Previous Article  |  Next Article 

Clinical and Diagnostic Laboratory Immunology, March 1999, p. 186-192, Vol. 6, No. 2
1071-412X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Protection against Influenza Virus Infection of Mice Fed Bifidobacterium breve YIT4064

Hisako Yasui,* Junko Kiyoshima, Tetuji Hori, and Kan Shida

Yakult Central Institute for Microbiological Research and Department of Microbiology, 1796 Yaho, Kunitachi-shi, Tokyo 186-8650, Japan

Received 22 September 1998/Returned for modification 22 October 1998/Accepted 2 December 1998

Mice fed Bifidobacterium breve YIT4064 and immunized orally with influenza virus were more strongly protected against influenza virus infection of the lower respiratory tract than ones immunized with influenza virus only. The number of mice with enhanced anti-influenza virus immunoglobulin G (IgG) in serum upon oral administration of B. breve YIT4064 and oral immunization with influenza virus was significantly greater than that upon oral immunization with influenza virus only. These findings demonstrated that the oral administration of B. breve YIT4064 increased anti-influenza virus IgG antibodies in serum and protected against influenza virus infection. The oral administration of B. breve YIT4064 may enhance antigen-specific IgG against various pathogenic antigens taken orally and induce protection against various virus infections.

* Corresponding author. Mailing address: Yakult Central Institute for Microbiological Research and Department of Microbiology, 1796 Yaho, Kunitachi-shi, Tokyo 186-8650, Japan. Phone: 81 42 577 8960. Fax: 81 42 577 3020.

Clinical and Diagnostic Laboratory Immunology, March 1999, p. 186-192, Vol. 6, No. 2
1071-412X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:



Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Antimicrob. Agents Chemother. Clin. Microbiol. Rev. Infect. Immun.
J. Clin. Microbiol. J. Virol. ALL ASM JOURNALS

Copyright © 1999 by the American Society for Microbiology. All rights reserved.