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 Previous Article

Clinical and Diagnostic Laboratory Immunology, January 2001, p. 206-208, Vol. 8, No. 1
1071-412X/01/$04.00+0   DOI: 10.1128/CDLI.8.1.206-208.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Porins and Lipopolysaccharide Induce Apoptosis in Human Spermatozoa

Fernanda Gorga,1,* Marilena Galdiero,1 Elisabetta Buommino,1 and Emilia Galdiero2

Istituto di Microbiologia, Facoltà di Medicina e Chirurgia, Seconda Università degli Studi di Napoli,1 and Dipartimento Fisiologia Generale ed Ambientale, Sezione Igiene e Microbiologia, Università degli Studi di Napoli Federico II,2 80138 Napoli, Italy

Received 16 March 2000/Returned for modification 14 August 2000/Accepted 10 October 2000

Treatment of human spermatozoa with porins or lipopolysaccharide (LPS) increases spontaneous apoptosis in these cells. Porins and LPS were extracted from Salmonella enterica serovar Typhimurium and Pasteurella multocida and were mixed with human spermatozoa for detection of levels of apoptosis.

* Corresponding author. Mailing address: Istituto di Microbiologia, Facoltà di Medicina e Chirurgia, Seconda Università degli Studi di Napoli, Larghetto S. Aniello a Caponapoli, 2, 80138 Napoli, Italy. Phone: 39 81-5665662. Fax: 39 81-5665663. E-mail: francesco.galdiero{at}unina2.it.

Clinical and Diagnostic Laboratory Immunology, January 2001, p. 206-208, Vol. 8, No. 1
1071-412X/01/$04.00+0   DOI: 10.1128/CDLI.8.1.206-208.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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  • Stouffs, K., Lissens, W., Verheyen, G., Van Landuyt, L., Goossens, A., Tournaye, H., Van Steirteghem, A., Liebaers, I. (2004). Expression pattern of the Y-linked PRY gene suggests a function in apoptosis but not in spermatogenesis. Mol Hum Reprod 10: 15-21 [Abstract] [Full Text]  
  • Hosseinzadeh, S., Pacey, A.A., Eley, A. (2003). Chlamydia trachomatis-induced death of human spermatozoa is caused primarily by lipopolysaccharide. J Med Microbiol 52: 193-200 [Abstract] [Full Text]  


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