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Clinical and Diagnostic Laboratory Immunology, March 2001, p. 437-440, Vol. 8, No. 2
1071-412X/01/$04.00+0   DOI: 10.1128/CDLI.8.2.437-440.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Development of a Novel Screen for Protease Inhibitors

L. Gillim,1 G. L. Gusella,1 J. Vargas Jr.,1 D. Marras,1 M. E. Klotman,1 and A. Cara2,*

Divisions of Infectious Disease and Nephrology, Mount Sinai School of Medicine, New York, New York,1 and Istituto Superiore di Sanita', Rome, Italy 001612

Received 17 July 2000/Returned for modification 5 September 2000/Accepted 14 November 2000

We have developed a novel plasmid-based, quantitative, in vitro screen to test the protease-inhibiting activities of existing and newly discovered agents.

* Corresponding author. Mailing address: c/o Mount Sinai School of Medicine, Division of Infectious Disease, Box 1090, 1 Gustave L. Levy Place, New York, NY 10029-6874. Phone: (212) 241-2950. Fax: (212) 534-3240. E-mail: acara{at}usa.net.

Clinical and Diagnostic Laboratory Immunology, March 2001, p. 437-440, Vol. 8, No. 2
1071-412X/01/$04.00+0   DOI: 10.1128/CDLI.8.2.437-440.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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