CVI Accepts, published online ahead of print on 14 October 2009
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Clin. Vaccine Immunol. doi:10.1128/CVI.00238-09
Copyright (c) 2009, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Prevalence of Human Papillomavirus 16 and 18 Neutralizing Antibodies in Prenatal British Columbia Women

Mel Krajden*, Karuna Karunakaran, Stacy So, Joel M. Palefsky, Rachna Sharma, Darrel Cook, Amanda Yu, Ron Chow, Simon Dobson, Gina S. Ogilvie, and Martin Petric

British Columbia Centre for Disease Control, Vancouver, Canada; University of British Columbia, Vancouver, Canada; Provincial Health Services Authority Laboratories, Vancouver, Canada; University of California San Francisco, San Francisco, USA; Children's and Women's Hospital, Vancouver, Canada

* To whom correspondence should be addressed. Email: mel.krajden{at}bccdc.ca.


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Abstract

HPV 16 and 18 neutralizing antibody (NAb) titers were measured in 1020 prenatal British Columbia women aged 15 to 39. HPV 16 and 18 NAb were detected in 183/1020 (17.9%) and 97/1020 (9.5%) respectively, and 39 (3.8%) had NAb to both types. Titers were similar across age strata.