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Clinical and Diagnostic Laboratory Immunology, May 2003, p. 479-480, Vol. 10, No. 3
1071-412X/03/$08.00+0     DOI: 10.1128/CDLI.10.3.479-480.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Lymphocyte Transformation Test for Medicinal Herbs Yields False-Positive Results for First-Visit Patients

Naoki Mantani,1,2* Toshiaki Kogure,1 Jun'ichi Tamura,3 Yutaka Shimada,2 and Katsutoshi Terasawa2

Departments of Integrated Japanese Oriental Medicine,1 General Medicine, Gunma University School of Medicine, Maebashi,3 Department of Japanese Oriental Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan2

Received 10 October 2002/ Returned for modification 4 December 2002/ Accepted 2 January 2003

We performed lymphocyte transformation tests (LTTs) for toki (angelicae radix) and ogon (scutellariae radix) on first-visit patients who had never taken Kampo medicines. LTTs for both herbs were positive in 12 of 14 patients, suggesting that LTTs for these herbs are unreliable for the diagnosis of Kampo medicine-induced liver injury.

* Corresponding author. Mailing address: Department of Integrated Japanese Oriental Medicine, Gunma University School of Medicine, 3-39-15 Showa-machi, Maebashi, Gunma 371-8511 Japan. Phone: 81-27-220-8666. Fax: 81-27-220-8666. E-mail: nmantani{at}showa.gunma-u.ac.jp.

Clinical and Diagnostic Laboratory Immunology, May 2003, p. 479-480, Vol. 10, No. 3
1071-412X/03/$08.00+0     DOI: 10.1128/CDLI.10.3.479-480.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.





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