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Clinical and Diagnostic Laboratory Immunology, May 2003, p. 483-484, Vol. 10, No. 3
1071-412X/03/$08.00+0     DOI: 10.1128/CDLI.10.3.483-484.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Serological Survey of Toscana Virus Infections in a High-Risk Population in Italy

Marcello Valassina,1* Melissa Valentini,1 Agostino Pugliese,2 Pier Egisto Valensin,1 and Maria Grazia Cusi1

Microbiology Section, Department of Molecular Biology, University of Siena, Siena,1 Department of Medical and Surgical Sciences, Clinical Microbiology Section, University of Turin, Turin, Italy2

Received 15 November 2002/ Returned for modification 10 January 2003/ Accepted 12 February 2003

Toscana virus is the most important agent responsible for meningitis in central Italy. We report a serosurveillance study, using an immunoenzymatic assay, of 360 serum samples harvested from a high-risk population occupationally exposed to Toscana virus in two regions of Italy, Tuscany and Piedmont. The results indicates a seroprevalence of Toscana virus of 77.2% in the forestry workers, particularly in the Tuscany region. This fact is strictly correlated with the ecological niches specific for the survival of Toscana virus arthropod vector.


* Corresponding author. Mailing address: Department of Molecular Biology, Microbiology Section, University of Siena, Via Laterina 8, 53100 Siena, Italy. Phone: 39 577-233850. Fax: 39 577-233870. E-mail: valassina{at}unisi.it.


Clinical and Diagnostic Laboratory Immunology, May 2003, p. 483-484, Vol. 10, No. 3
1071-412X/03/$08.00+0     DOI: 10.1128/CDLI.10.3.483-484.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.