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Clinical and Diagnostic Laboratory Immunology, July 2003, p. 718-720, Vol. 10, No. 4
1071-412X/03/$08.00+0     DOI: 10.1128/CDLI.10.4.718-720.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Hepatitis B Virus DNA in Sera of Blood Donors and of Patients Infected with Hepatitis C Virus and Human Immunodeficiency Virus

Fernando Lopes Gonçales Jr.,1* Josiane Silveira Felix Pereira,1 Claudia da Silva,1 Glaucimari Roberto Thomaz,1 Maria Helena Postal Pavan,1 Viviane Cristina Fais,1 Luis Alberto Magna,2 and Neiva Sellan Lopes Gonçales1,3

Grupo de Estudos das Hepatites, Disciplina de Moléstias Infecciosas,1 Departamento de Genética Médica, Faculdade de Ciências Médicas,2 Centro de Hematologia e Hemoterapia, UNICAMP, Campinas, SP, Brazil3

Received 10 January 2003/ Returned for modification 9 April 2003/ Accepted 8 May 2003

With the use of PCR, we searched for hepatitis B virus (HBV) DNA in serum samples from 415 HBsAg-negative, anti-HBc-positive patients: 150 were blood donors, 106 had only hepatitis C virus (HCV) infection, and 159 had human immunodeficiency virus (HIV) infection (of which 88 were HCV positive and 71 were HCV negative). HBV DNA was detected in 4% of blood donors, 3.4% of HIV- and HCV-positive patients, and 24% of HCV-positive patients.

* Corresponding author. Mailing address: Grupo de Estudos das Hepatites, Disciplina de Moléstias Infecciosas, Departamento de Clínica Médica, Faculdade de Ciências Médicas, UNICAMP, Av Dr Romeu Tórtima, 725, CEP 130843-885, Barão Geraldo, Campinas, SP, Brazil. Phone and fax: 55-19-3289-4513. E-mail: flgj{at}uol.com.br.

Clinical and Diagnostic Laboratory Immunology, July 2003, p. 718-720, Vol. 10, No. 4
1071-412X/03/$08.00+0     DOI: 10.1128/CDLI.10.4.718-720.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.





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