This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Tugume, S. B.
Right arrow Articles by Katongole-Mbidde, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tugume, S. B.
Right arrow Articles by Katongole-Mbidde, E.

 Previous Article  |  Next Article 

Clinical and Diagnostic Laboratory Immunology, Mar 1995, 233-235, Vol 2, No. 2
Copyright © 1995 by the American Society for Microbiology. All rights reserved.

Hematological reference ranges among healthy Ugandans

SB Tugume, EM Piwowar, T Lutalo, PN Mugyenyi, RM Grant, FW Mangeni, K Pattishall and E Katongole-Mbidde
Joint Clinical Research Centre, Makerere University Medical School, Kampala, Uganda.

Reference values are essential for the interpretation of hematologic data in clinical practice and research studies. Symptom-free human immunodeficiency virus antibody-negative Ugandan adults (183 subjects, aged 15 to 74 years, 37.7% women and 62.3% men) were studied to establish hematological reference ranges. The central 95% areas under the distribution curves were 1,453 to 4,448 cells per microliters for the absolute lymphocyte count, 559 to 2,333 cells per microliters for the absolute CD4 count, 253 to 1,396 cells per microliters for the absolute CD8 count, and 0.68 to 4.4 for the CD4/CD8 ratio. Women had significantly higher mean absolute lymphocyte counts (2,826 versus 2,568/microliters), absolute CD4 counts (1,425 versus 1,154/microliters) and absolute CD4/CD8 ratios (2.58 versus 1.88) than did men. These reference ranges differ from those reported for populations outside Africa.


This article has been cited by other articles:

  • Aina, O., Dadik, J., Charurat, M., Amangaman, P., Gurumdi, S., Mang, E., Guyit, R., Lar, N., Datong, P., Daniyam, C., Kanki, P., Abimiku, A., for the Institute of Human Virology/Plateau State, (2005). Reference Values of CD4 T Lymphocytes in Human Immunodeficiency Virus-Negative Adult Nigerians. CVI 12: 525-530 [Abstract] [Full Text]  
  • Bussmann, H., Wester, C. W., Masupu, K. V., Peter, T., Gaolekwe, S. M., Kim, S., Reich, A. M., Ahn, S., Wu, Y., Thior, I., Essex, M., Marlink, R. (2004). Low CD4+ T-Lymphocyte Values in Human Immunodeficiency Virus-Negative Adults in Botswana. CVI 11: 930-935 [Abstract] [Full Text]  
  • Lugada, E. S., Mermin, J., Kaharuza, F., Ulvestad, E., Were, W., Langeland, N., Asjo, B., Malamba, S., Downing, R. (2004). Population-Based Hematologic and Immunologic Reference Values for a Healthy Ugandan Population. CVI 11: 29-34 [Abstract] [Full Text]  
  • Menard, D., Mandeng, M. J., Tothy, M. B., Kelembho, E. K., Gresenguet, G., Talarmin, A. (2003). Immunohematological Reference Ranges for Adults from the Central African Republic. CVI 10: 443-445 [Abstract] [Full Text]  
  • Kassu, A., Tsegaye, A., Petros, B., Wolday, D., Hailu, E., Tilahun, T., Hailu, B., Roos, M. T. L., Fontanet, A. L., Hamann, D., De Wit, T. F. R. (2001). Distribution of Lymphocyte Subsets in Healthy Human Immunodeficiency Virus-Negative Adult Ethiopians from Two Geographic Locales. CVI 8: 1171-1176 [Abstract] [Full Text]  
  • Tsegaye, A., Messele, T., Tilahun, T., Hailu, E., Sahlu, T., Doorly, R., Fontanet, A. L., Rinke de Wit, T. F. (1999). Immunohematological Reference Ranges for Adult Ethiopians. CVI 6: 410-414 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»