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Clinical and Diagnostic Laboratory Immunology, May 1999, p. 425-426, Vol. 6, No. 3
1071-412X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Identification of a Peptide from Mammal Albumins Responsible for Enhanced Pigment Production by Group B Streptococci

Manuel Rosa-Fraile,1,* Antonio Sampedro,1 Javier Varela,2 Marisa Garcia-Peña,1 and Guillermo Gimenez-Gallego2

Microbiology Service, Virgen de las Nieves Hospital, 18014 Granada,1 and Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Cientificas, 28006 Madrid,2 Spain

Received 3 August 1998/Returned for modification 2 December 1998/Accepted 19 January 1999

The peptide from peptones responsible for enhanced pigment production by Streptococcus agalactiae in culture media has been isolated from a peptic digest of human albumin and has been identified as Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe. The related heptapeptide lacking the N-terminal Ile also had pigment-enhancing activity. A sequence similarity search showed that these sequences are present only in mammal albumins.

* Corresponding author. Mailing address: Servicio de Microbiología, Hospital Virgen de las Nieves, 18014 Granada, Spain. Phone: 34-958-241109. Fax: 34-958-241282 or 34-958-241245. E-mail: delarosa{at}cica.es.

Clinical and Diagnostic Laboratory Immunology, May 1999, p. 425-426, Vol. 6, No. 3
1071-412X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Rosa-Fraile, M., Rodriguez-Granger, J., Camacho-Munoz, E., Sampedro, A. (2005). Use of Unmodified Starches and Partial Removal of Serum To Improve Granada Medium Stability. J. Clin. Microbiol. 43: 1989-1991 [Abstract] [Full Text]  
  • De La Rosa-Fraile, M. (2003). Granada Agar Sensitivity and Detection of Group B Streptococcus. J. Clin. Microbiol. 41: 4007-4007 [Full Text]  
  • Rosa-Fraile, M., Sampedro, A., Rodríguez-Granger, J., García-Peña, M. L., Ruiz-Bravo, A., Haïdour, A. (2001). Pigment Production by Streptococcus agalactiae in Quasi-Defined Media. Appl. Environ. Microbiol. 67: 473-474 [Abstract] [Full Text]  


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