This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Willman, J. H.
Right arrow Articles by Litwin, C. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Willman, J. H.
Right arrow Articles by Litwin, C. M.

 Previous Article  |  Next Article 

Clinical and Diagnostic Laboratory Immunology, July 1999, p. 615-616, Vol. 6, No. 4
1071-412X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Heterophile Antibodies to Bovine and Caprine Proteins Causing False-Positive Human Immunodeficiency Virus Type 1 and Other Enzyme-Linked Immunosorbent Assay Results

Joseph H. Willman, Thomas B. Martins, Troy D. Jaskowski, Harry R. Hill, and Christine M. Litwin*

Division of Clinical Pathology, Department of Pathology, and Department of Pediatrics, University of Utah, ARUP Laboratories and the ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah 84132

Received 9 February 1999/Returned for modification 1 April 1999/Accepted 13 April 1999

Heterophile antibodies are a well-recognized cause of erroneous results in immunoassays. We describe here a 22-month-old child with heterophile antibodies reactive with bovine serum albumin and caprine proteins causing false-positive results to human immunodeficiency virus type 1 and other infectious serology testing.

* Corresponding author. Mailing address: Department of Pathology, University of Utah, 50 N. Medical Dr., Salt Lake City, UT 84132. Phone: (801) 585-6864. Fax: (801) 585-6285. E-mail: Christine_Litwin{at}hlthsci.med.utah.edu.

Clinical and Diagnostic Laboratory Immunology, July 1999, p. 615-616, Vol. 6, No. 4
1071-412X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Roongsritong, C., Warraich, I., Bradley, C. (2004). Common Causes of Troponin Elevations in the Absence of Acute Myocardial Infarction: Incidence and Clinical Significance. Chest 125: 1877-1884 [Abstract] [Full Text]  
  • Martins, T. B., Pasi, B. M., Litwin, C. M., Hill, H. R. (2004). Heterophile Antibody Interference in a Multiplexed Fluorescent Microsphere Immunoassay for Quantitation of Cytokines in Human Serum. CVI 11: 325-329 [Abstract] [Full Text]  
  • Kim, W. J., Laterza, O. F., Hock, K. G., Pierson-Perry, J. F., Kaminski, D. M., Mesguich, M., Braconnier, F., Zimmermann, R., Zaninotto, M., Plebani, M., Hanna, A., Cembrowski, G. S., Scott, M. G. (2002). Performance of a Revised Cardiac Troponin Method That Minimizes Interferences from Heterophilic Antibodies. Clin. Chem. 48: 1028-1034 [Abstract] [Full Text]  
  • Revelen, R., Bordron, A., Dueymes, M., Youinou, P., Arvieux, J. (2000). False Positivity in a Cyto-ELISA for Anti-Endothelial Cell Antibodies Caused by Heterophile Antibodies to Bovine Serum Proteins. Clin. Chem. 46: 273-278 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»