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Clinical and Diagnostic Laboratory Immunology, November 1999, p. 981-982, Vol. 6, No. 6
1071-412X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Declining Immunoglobulin A Production in Prostates of Men with AIDS

Henry J. Carson1,* and Nathan E. Lueck2

Department of Pathology, Mercy Medical Center, Cedar Rapids,1 and Grinnell College, Grinnell,2 Iowa

Received 16 August 1999/Accepted 1 September 1999

We studied immunoglobulin A production (IgA) in prostates of men with AIDS. Prostate sections from AIDS patients and human immunodeficiency virus-negative men were stained for IgA with immunoperoxidase. Prostate sections from nondiseased men were positive for IgA, while prostate sections from AIDS patients were essentially negative for IgA. Diminishing secretory IgA production may represent a characteristic of AIDS.

* Corresponding author. Mailing address: Department of Pathology, Mercy Medical Center, 701 10th Street S.E., Cedar Rapids, IA 52403. Phone: (319) 398-6831. Fax: (319) 398-6004. E-mail: hjcmd{at}earthlink.net.

Clinical and Diagnostic Laboratory Immunology, November 1999, p. 981-982, Vol. 6, No. 6
1071-412X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.




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