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Clinical and Diagnostic Laboratory Immunology, March 2000, p. 296-297, Vol. 7, No. 2
1071-412X/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Phagocytic Function of Monocytes in Children with Human Immunodeficiency Virus Type 1 Infection

Gratiela Tardei,1,* Dan Duiculescu,2 Christian Capo,3 Carmen-Cristina Diaconu,1 Adrian Mutiu,1 Jean-Louis Mege,3 and Costin Eugen Cernescu1

St. S. Nicolau Institute of Virology1 and Victor Babes Hospital of Infectious and Tropical Diseases,2 Bucharest, Romania, and Unité des Rickettsies, CNRS UPRESA 6020, Faculté de Médecine, Marseille, France3

Received 22 July 1999/Returned for modification 30 September 1999/Accepted 14 December 1999

We investigated the phagocytic function of monocytes in 7- to 10-year-old children horizontally infected with human immunodeficiency virus type 1 (HIV-1) in comparison to that in healthy sex- and age-matched controls. CR3-mediated phagocytosis was increased in patients with HIV-associated pulmonary tuberculosis, independently of CD4 counts and p24 antigenemia.

* Corresponding author. Mailing address: St. S. Nicolau Institute of Virology, sos. Mihai Bravu 285, Bucharest 79650, Romania. Phone: 401 324 25 90. Fax: 401 321 18 13. E-mail: gtardei{at}hotmail.com.

Clinical and Diagnostic Laboratory Immunology, March 2000, p. 296-297, Vol. 7, No. 2
1071-412X/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.




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