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Clinical and Diagnostic Laboratory Immunology, September 2000, p. 813-816, Vol. 7, No. 5
1071-412X/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Hepatitis E Virus Immunoglobulin G Antibodies in Different Populations in Campinas, Brazil

Neiva S. L. Gonçales,1 João Renato R. Pinho,2,* Regina C. Moreira,2 Cláudia P. Saraceni,2 Ângela M. M. Spina,2 Raquel B. Stucchi,3 Aírton D. Ribeiro Filho,4 Luís A. Magna,5 and Fernando L. Gonçales Júnior3

Disciplina de Moléstias Infecciosas3 and Ambulatório Municipal de DST/AIDS,4 Departamento de Genética Médica, Faculdade de Ciéncias Médicas,5 and Centro de Hematologia e Hemoterapia,1 UNICAMP, Campinas, and Serviço de Virologia, Instituto Adolfo Lutz,2 São Paulo, Brazil

Received 16 March 2000/Returned for modification 8 June 2000/Accepted 12 July 2000

The seroprevalence of anti-hepatitis E virus (HEV) antibodies was investigated by enzyme immunoassay in 205 volunteer blood donors, 214 women who attended a center for anonymous testing for human immunodeficiency virus (HIV) infection, and 170 hospital employees in Campinas, a city in southeastern Brazil. The prevalence of anti-HEV antibodies ranged from 2.6% (3 of 117) in health care professionals to 17.7% (38 of 214) in women who considered themselves at risk for HIV. The prevalence of anti-HEV antibodies in health care professionals was not significantly different from that in healthy blood donors (3.0%, 5 of 165) and blood donors with raised alanine aminotransferase levels (7.5%, 3 of 40). The prevalence of anti-HEV antibodies (13.2%, 7 of 53) in cleaning service workers at a University hospital was similar to that among women at risk for HIV infection. These results suggest that HEV is circulating in southeastern Brazil and that low socioeconomic status is an important risk factor for HEV infection in this region.

* Corresponding author. Mailing address: Serviço de Virologia, Instituto Adolfo Lutz, Ave. Doutor Arnaldo 355, 01246-902, São Paulo-SP, Brazil. Phone: 55 11 3068 2911. Fax: 55 11 280 3753. E-mail: jrrpinho{at}usp.br.

Clinical and Diagnostic Laboratory Immunology, September 2000, p. 813-816, Vol. 7, No. 5
1071-412X/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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