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Clinical and Diagnostic Laboratory Immunology, September 2000, p. 845-849, Vol. 7, No. 5
1071-412X/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Prevalence and Phylogenetic Analysis of TT Virus DNA in Western India

V. A. Arankalle,* S. S. Gandhe, T. M. Deshmukh, M. S. Chadha, and A. M. Walimbe

Hepatitis Division, National Institute of Virology, Pune, India

Received 6 December 1999/Returned for modification 8 May 2000/Accepted 31 May 2000

In western India, TT virus (TTV) DNA positivity varied from 6.7% (5 of 75) in chronic hepatitis patients to 24.4% (10 of 41) in hemophiliacs; 7.4% (4 of 54) of voluntary blood donors had circulating TTV DNA. Phylogenetic analysis revealed a predominance of genotype 1a. In India, TTV is transmitted mainly by nonparenteral routes and is not an important cause of chronic liver diseases.

* Corresponding author. Mailing address: Hepatitis Division, National Institute of Virology, Indian Council of Medical Research, 20-A, Dr Ambedkar Rd., Pune, India 411001. Phone: 91 212 627301. Fax: 91 212 622669. E-mail: aarankalle{at}hotmail.com.

Clinical and Diagnostic Laboratory Immunology, September 2000, p. 845-849, Vol. 7, No. 5
1071-412X/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.




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