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Clinical and Diagnostic Laboratory Immunology, September 2001, p. 1012-1014, Vol. 8, No. 5
1071-412X/01/$04.00+0   DOI: 10.1128/CDLI.8.5.1012-1014.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Serum Antibody Response to Polysaccharides in Children with Recurrent Respiratory Tract Infections

Alberto López-Yap,1 Arturo Abdelnour,2,* Bruno Lomonte,3 and Oscar Porras2

Laboratorio Clínico, Caja de Seguro Social de Panamá,1 Servicio de Inmunología, Hospital Nacional de Niños "Dr. Carlos Sáenz Herrera,"2 and Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica,3 San José, Costa Rica

Received 14 August 2000/Returned for modification 4 January 2001/Accepted 17 May 2001

We evaluated children (15-months old and older) with recurrent upper respiratory tract infections and normal levels of immunoglobulins in serum for specific polysaccharide immunodeficiency using an enzyme-linked immunosorbent assay method. Results showed that of 12 patients vaccinated with Act-HIB vaccine, one did not develop specific antibodies to Haemophilus influenzae type b, demonstrating that such immunodeficiency is present in Costa Rican children.

* Corresponding author. Mailing address: Servicio de Inmunología, Hospital Nacional de Niños "Dr. Carlos Sáenz Herrera," San José, Costa Rica. Phone and fax: (506) 223-51-25. E-mail: aabdelnour{at}hnn.sa.cr or alberto68{at}latinmail.com.

Clinical and Diagnostic Laboratory Immunology, September 2001, p. 1012-1014, Vol. 8, No. 5
1071-412X/01/$04.00+0   DOI: 10.1128/CDLI.8.5.1012-1014.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.




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