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Clinical and Diagnostic Laboratory Immunology, September 2001, p. 1015-1017, Vol. 8, No. 5
1071-412X/01/$04.00+0   DOI: 10.1128/CDLI.8.5.1015-1017.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Serum Immunoglobulin G Antibody Responses to Bordetella pertussis Lipooligosaccharide and B. parapertussis Lipopolysaccharide in Children with Pertussis and Parapertussis

Birger Trollfors,1,* Teresa Lagergård,2 John Taranger,1 Elisabet Bergfors,1 Rachel Schneerson,3 and John B. Robbins3

The Göteborg Pertussis Vaccine Study, The Göteborg Primary Health Care System,1 and the Department of Medical Microbiology and Immunology, Göteborg University,2 Göteborg, Sweden, and the National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 208923

Received 2 February 2001/Returned for modification 27 March 2001/Accepted 21 May 2001

Serum immunoglobulin G (IgG) antibodies against the lipooligosaccharide (LOS) of Bordetella pertussis and the lipopolysaccharide (LPS) of Bordetella parapertussis were measured by enzyme-linked immunosorbent assay in paired sera from 40 children with pertussis and 14 with parapertussis. Wide differences in the individual responses were noted. Both anti-LOS and -LPS IgG levels increased significantly in the children with pertussis, as did anti-LPS but not anti-LOS in those with parapertussis.

* Corresponding author: Birger Trollfors, Department of Pediatrics, Sahlgrenska University Hospital-East, S-416 85 Göteborg, Sweden. Phone: 46 31 3434000. Fax: 46 31 84 30 10. E-mail: birger.trollfors{at}vgregion.se.

Clinical and Diagnostic Laboratory Immunology, September 2001, p. 1015-1017, Vol. 8, No. 5
1071-412X/01/$04.00+0   DOI: 10.1128/CDLI.8.5.1015-1017.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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