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Clinical and Diagnostic Laboratory Immunology, November 2001, p. 1277-1278, Vol. 8, No. 6
1071-412X/01/$04.00+0   DOI: 10.1128/CDLI.8.6.1277-1278.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Skin Test Reactivity and Cellular Immune Responses to Mycobacterium avium Sensitin in AIDS Patients at Risk for Disseminated M. avium Infection

C. Fordham von Reyn,1,* Paige L. Williams,2 Howard M. Lederman,3 J. Allen McCutchan,4 Susan L. Koletar,5 Robert L. Murphy,6 Susan E. Cohn,7 Thomas Evans,7 Alison E. Heald,8 Dodi Colquhoun,2 Ehab L. Bassily,2 and Judith S. Currier9

Infectious Disease Section, Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire1; Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts2; Department of Pediatrics, Johns Hopkins Hospital, Baltimore, Maryland3; Treatment Center, University of California, San Diego, San Diego,4 and CARE Center, University of California, Los Angeles, Los Angeles,9 California; Ohio State University Hospitals, Columbus, Ohio5; Northwestern University Medical School, Chicago, Illinois6; University of Rochester Medical Center, Rochester, New York7; and Duke University Medical Center, Durham, North Carolina8

Received 18 May 2001/Returned for modification 15 August 2001/Accepted 5 September 2001

Skin tests and lymphocyte proliferation assays (LPA) were performed with Mycobacterium avium sensitin on patients with AIDS. Among 139 subjects, 13% had positive skin test results and 32% had positive LPA results. The LPA may be a more sensitive indicator of prior M. avium infection in this population.

* Corresponding author. Mailing address: Infectious Disease Section, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756. Phone: (603) 650-8840. Fax: (603) 650-6199. E-mail: c.fordham.von.reyn{at}hitchcock.org.

Clinical and Diagnostic Laboratory Immunology, November 2001, p. 1277-1278, Vol. 8, No. 6
1071-412X/01/$04.00+0   DOI: 10.1128/CDLI.8.6.1277-1278.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.




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