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Clinical and Diagnostic Laboratory Immunology, January 2002, p. 182-183, Vol. 9, No. 1
1071-412X/01/$04.00+0     DOI: 10.1128/CDLI.9.1.182-183.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Feed a Cold, Starve a Fever?

Gijs R. van den Brink,* Daniëlle E. M. van den Boogaardt, Sander J. H. van Deventer, and Maikel P. Peppelenbosch

Laboratory for Experimental Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands

Received 20 June 2001/ Returned for modification 5 September 2001/ Accepted 21 September 2001

An English old wives’ tale advises us to "feed a cold and starve a fever." Here we report that the nutritional status modulates the T helper 1 (Th1)-Th2 balance of activated T cells in human volunteers. Food intake resulted in increased levels of gamma interferon production, whereas food deprivation stimulated interleukin-4 release.

* Corresponding author. Mailing address: Laboratory for Experimental Internal Medicine, Room G2-130, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. Phone: 31-20-5668781. Fax: 31-20-6977192. E-mail: g.r.vandenbrink{at}amc.uva.nl.

Clinical and Diagnostic Laboratory Immunology, January 2002, p. 182-183, Vol. 9, No. 1
1071-412X/01/$04.00+0     DOI: 10.1128/CDLI.9.1.182-183.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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