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Clinical and Diagnostic Laboratory Immunology, March 2002, p. 489-490, Vol. 9, No. 2
1071-412X/02/$04.00+0     DOI: 10.1128/CDLI.9.2.489-490.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Preconception Seroconversion and Maternal Seronegativity at Delivery Do Not Rule Out the Risk of Congenital Toxoplasmosis

C. Chemla,1 I. Villena,1 D. Aubert,1 P. Hornoy,2 D. Dupouy,3 B. Leroux,3 J. P. Bory,4 and J. M. Pinon1*

Divisions of Parasitology,1 Imagery,2 Pediatrics,3 Gynecology, Reims Toxoplasmosis Group, Laboratoire de Parasitologie-Mycologie, Centre Hospitalier Universitaire, EA2070, IFR 53, Reims 51092, France4

Received 20 August 2001/ Returned for modification 6 November 2001/ Accepted 5 December 2001

We describe two unusual cases of congenital toxoplasmosis, one occurring after preconception maternal infection with cervical adenopathies and the other occurring after maternal infection at the very end of pregnancy with maternal seronegativity at delivery. These documented cases of congenital toxoplasmosis demonstrate the value of extending the serologic monitoring period during pregnancy, according to the individual clinical context.

* Corresponding author. Mailing address: Laboratoire de Parasitologie-Mycologie, Hôpital Maison Blanche, 45 rue Cognacq Jay, 51092 Reims, France. Phone: (33) 3.26.78.42.20. Fax: (33) 3.26.78.73.28. E-mail: jmpinon{at}chu-reims.fr.

Clinical and Diagnostic Laboratory Immunology, March 2002, p. 489-490, Vol. 9, No. 2
1071-412X/02/$04.00+0     DOI: 10.1128/CDLI.9.2.489-490.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Flori, P., Tardy, L., Patural, H., Bellete, B., Varlet, M.-N., Hafid, J., Raberin, H., Sung, R. T. M. (2004). Reliability of Immunoglobulin G Antitoxoplasma Avidity Test and Effects of Treatment on Avidity Indexes of Infants and Pregnant Women. CVI 11: 669-674 [Abstract] [Full Text]  


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