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Clinical and Diagnostic Laboratory Immunology, November 2002, p. 1398-1399, Vol. 9, No. 6
1071-412X/02/$04.00+0     DOI: 10.1128/CDLI.9.6.1398-1399.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Coombs Antiglobulin Test Using Brucella abortus 99 as Antigen To Detect Incomplete Antibodies Induced by B. abortus RB51 Vaccine in Cattle

Franco Ciuchini,* Rosanna Adone, and Paolo Pasquali

Laboratorio di Medicina Veterinaria, Istituto Superiore di Sanità, 00161 Rome, Italy

Received 6 March 2002/ Returned for modification 16 April 2002/ Accepted 18 June 2002

This study showed that vaccination of cattle with Brucella abortus rough strain RB51 induces incomplete antibodies that can be detectable by a Coombs antiglobulin test using the B. abortus 99 smooth strain.


* Corresponding author. Mailing address: Istituto Superiore di Sanità, Laboratorio di Medicina Veterinaria, Viale Regina Elena 299, 00161 Rome, Italy. Phone: 39-06-49902326. Fax: 39-06-49387077. E-mail: franco.ciuchini{at}iss.it.


Clinical and Diagnostic Laboratory Immunology, November 2002, p. 1398-1399, Vol. 9, No. 6
1071-412X/02/$04.00+0     DOI: 10.1128/CDLI.9.6.1398-1399.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.